Clinical Sites | North American Mitochondrial Disease Consortium

Akron Children's Hospital

Clinic:

215 W. Bowery Street, CPB 4th Floor
Akron, Ohio 44308

Website:

https://www.akronchildrens.org/locations/Neurology-Akron.html

Studies:

Recruiting

7401: North American Mitochondrial Disease Consortium Patient Registry and Biorespository

7405: Natural History of Alpers-Huttenlocher Syndrome

Baylor College of Medicine - Texas Children's Hospital

Clinic:

Department of Molecular and Human Genetics, Mark Wallace Tower, Suite 1560, 6701 Fannin St
Houston, Texas 77030

Website:

https://www.bcm.edu/

Studies:

Recruiting

7401: North American Mitochondrial Disease Consortium Patient Registry and Biorespository

7416: L-Citrulline treatment of nitric oxide deficiency in MELAS: a Phase I dose-finding and safety study

Establish the maximum tolerable dose of L-citrulline in patients with MELAS.

Boston Children's Hospital

Clinic:

Department of Neurology, 300 Longwood Avenue
Boston, Massachusetts 02115

Website:

https://www.childrenshospital.org/

Studies:

Recruiting

7401: North American Mitochondrial Disease Consortium Patient Registry and Biorespository

Case Western Reserve University

Clinic:

Cleveland Clinic, 9500 Euclid Ave, S60
Cleveland, Ohio 44195

Website:

https://case.edu/

Studies:

Recruiting

7401: North American Mitochondrial Disease Consortium Patient Registry and Biorespository

Children's Hospital Colorado

Clinic:

Clinical Genetics and Metabolism, Mailstop 8400, 13123 E 16th Avenue, Education 2 South, L28-4122
Aurora, Colorado 80045

Website:

https://www.childrenscolorado.org/locations/anschutz-medical-campus-aurora/

Studies:

Recruiting

7401: North American Mitochondrial Disease Consortium Patient Registry and Biorespository

Children's Hospital of Philadelphia

Clinic:

Division of Human Genetics, ARC 1002c, 3615 Civic Center Blvd
Philadelphia, Pennsylvania 19104

Website:

https://www.chop.edu/

Studies:

Recruiting

7401: North American Mitochondrial Disease Consortium Patient Registry and Biorespository

7426: Harnessing resilience in adults with primary mitochondrial disease: A pilot study investigating the feasibility of the Promoting Resilience in Stress Management (PRISM) and clinical-focused narrative (CFN) interventions

Evaluate PRISM and CFN interventions in adults with primary mitochondrial disease (PMD). Develop basic statistical pilot information to develop a first efficacy study.

Children's Hospital of Pittsburgh

Clinic:

4401 Penn Avenue
Pittsburgh, Pennsylvania 15224

Website:

https://www.chp.edu/

Studies:

Recruiting

7401: North American Mitochondrial Disease Consortium Patient Registry and Biorespository

7413: Advanced Genetic Study and Pilot Newborn Screening for Disorders of Pyruvate Metabolism

Continue the longitudinal natural history study of phenotypic and genetic features of PDC deficiencies by integration with the NAMDC Patient Data Registry and Biorepository, recruitment of a broad group of subjects, and detailed longitudinal follow-up, to identify and objective measurable clinically relevant outcomes, biomarkers, and responses to treatments.